Superoxide Dismutases and Superoxide Reductases
نویسندگان
چکیده
منابع مشابه
Superoxide Dismutases and Superoxide Reductases
Yuewei Sheng,† Isabel A. Abreu,*,‡,§ Diane E. Cabelli,* Michael J. Maroney,* Anne-Frances Miller,* Miguel Teixeira,*,‡ and Joan Selverstone Valentine*,†,∇ †Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California 90095, United States ‡Instituto de Tecnologia Química e Bioloǵica Antońio Xavier, Universidade Nova de Lisboa, Av. da Repub́lica, 2780-157...
متن کاملSuperoxide radical and superoxide dismutases.
O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH.. SODs inhibit such HO. production by scavengingO2-, but Cu, ZnSODs, by virtue of a nonspecific peroxidase activity, may peroxidize spin trapping agents and thus give the appearance of catalyzing OH. production from H2O2. There is a glycosylate...
متن کاملOxygen Stress and Superoxide Dismutases.
The accumulation of dioxygen in Earth's atmosphere allowed for the evolution of aerobic organisms that use O2 as the terminal electron acceptor, thus providing a higher yield of energy compared with fermentation and anaerobic respiration. For example, in aerobic metabolism, the complete breakdown of one molecule of glucose yields a total of 38 molecules of ATP, whereas the anaerobic breakdown o...
متن کاملProkaryotic Cu,Zn superoxide dismutases.
The Cu,ZnSODs (Cu,Zn superoxide dismutases) comprise a class of ubiquitous metalloenzymes that catalyse the dismutation of the superoxide radical anion into oxygen and hydrogen peroxide. The dismutation reaction involves two successive encounters of the superoxide anion with a catalytic copper centre hosted by the enzyme at the dead end of a narrow protein channel. Cu,ZnSOD is found in all euka...
متن کاملSuperoxide dismutases in parasitoids' venom
Background: Endoparasitoid wasps inject venom proteins at oviposition to alter host immunity. Results: The venom of Leptopilina boulardi but not of a related species contains an active extracellular SOD. Recombinant SODs inhibit the Drosophila host phenoloxidase activity. Conclusion: An extracellular SOD is secreted and active in an insect fluid. Significance: SODs may be used as immune suppres...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical Reviews
سال: 2014
ISSN: 0009-2665,1520-6890
DOI: 10.1021/cr4005296